Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) comes from certain types of mushrooms found on nearly every continent.1 The mushrooms, which are also known as shrooms or magic mushrooms, are typically consumed dried or powdered. Psilocybin is part of a group of drugs called psychedelics—or hallucinogens—that have the potential to change a person’s sense of reality, leading them to see, hear, and feel things that are not happening in real life, or to experience reality in a different way.
“Mushrooms hold the secrets to the universe, to life on our planet, and the core of our being.” ~ Paul Stamets
Psilocybin is a powerful psychoactive substance that can cause intense psychological effects and should only be used under the guidance of a trained professional in a safe, controlled setting. The use of psilocybin may pose significant risks, especially for individuals with underlying mental health conditions, and may result in legal consequences in regions where it remains prohibited. This information is provided for educational purposes only and is not intended as medical or legal advice. Please consult with a licensed healthcare provider before considering the use of psilocybin or any other psychedelic substance.
Some people report taking magic mushrooms on their own hoping to achieve the same results, though additional research is needed to support this outcome.
People have been using mushrooms that contain psilocybin for thousands of years, including in religious rituals. Today, some people use the mushrooms in the hopes of having a unique, interesting, enlightening, and/or spiritual experience. Others take very small amounts of the substance regularly, a practice called microdosing, trying to improve their mental state and productivity.
Psilocybin is a chemical in certain types of mushrooms that grow on nearly every continent. The mushrooms have a long history of use in traditional ceremonies. Some people use them recreationally or to try to improve their mental health, although researchers still have much to learn about psilocybin’s potential uses as a medicine.
Proposition 122, also known as the Natural Medicine Health Act, was passed by Colorado voters in November 2022. This legislation decriminalizes the personal use, possession, growth, and sharing of certain natural psychedelic substances, including psilocybin, for adults 21 and older. The proposition aims to create a regulated system for licensed therapeutic centers where individuals can access these substances under supervision.
Decriminalization: Adults 21 and older are allowed to possess, use, grow, and gift certain psychedelics, such as psilocybin and psilocyn (from “magic mushrooms”) as well as other natural substances like mescaline (excluding peyote), ibogaine, and DMT.
Regulated Therapeutic Use: The state will establish licensed healing centers by 2024 where trained facilitators can guide patients through psychedelic experiences. The first phase focuses on psilocybin, with options to expand to other substances by 2026.
Healing Centers and Therapy: Trained facilitators at licensed centers will help individuals engage in supervised sessions for mental health purposes. The goal is to provide a controlled environment for safe use in therapeutic settings.
State Oversight: The Department of Regulatory Agencies in Colorado is responsible for setting up and regulating these centers, ensuring standards are met for safe and effective use.
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